Distinct spectrum of ciliopathic diseases results from de novoTUBB4B variants through differential effects on organelle-specific microtubules

ABSTRACT: We establish a necessary and non-redundant function for TUBB4B in building centrioles and axonemes of multiciliated cells placing ciliopathies more broadly into human tubulinopathies.  

ORGANISM(S): Homo sapiens

PROVIDER: GSE214070 | GEO | 2023/09/27

REPOSITORIES: GEO