Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons

ABSTRACT: We demonstrate in mice that perinatal SERT expression in glutamatergic pyramidal neurons in the hippocampus and mPFC modulates sexually dimorphic gene expression during hippocampal circuit assembly and is a source for sex-biased susceptibilities to cognitive and behavioral impairments.

ORGANISM(S): Mus musculus

PROVIDER: GSE214392 | GEO | 2022/10/01

REPOSITORIES: GEO