Transcriptomics

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Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol


ABSTRACT: SURF4 is a cargo receptor that has been implicated in the intracellular trafficking of PCSK9 and APOB - proteins involved in cholesterol transport and metabolism. We generated hepatic SURF4-deficient mice (Surf4(fl/fl) Alb-Cre+) to investigate the physiologic role of SURF4 in vivo

ORGANISM(S): Mus musculus

PROVIDER: GSE214393 | GEO | 2022/09/30

REPOSITORIES: GEO

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