Effect of Vortioxetine treatment on gene expression of LN-229 glioblastoma cells over time

ABSTRACT: The atypical antidepressant Vortioxetine represents the most effective neuroactive drug with anti-glioblastoma efficacy across glioblastoma patient samples and model systems. To closer examine the temporal dynamics of Vortioxetine, we performed in-depth transcriptomic profiling of LN-229 cells following Vortioxetine treatment. We performed gene expression profiling analysis using data obtained from RNA-seq across 6 different time points during the 24 hours following Vortioxetine treatment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE214968 | GEO | 2024/07/29

REPOSITORIES: GEO