Self-organizing in vitro mouse neural tube organoids mimic embryonic development

ABSTRACT: Self-elongating neural tube organoids recapitulate key aspects of the morphology, anterior-posterior patterning, neural crest emergence and neural differentiation of mouse embryo in vivo by self-organization. We used single-cell RNA sequencing (scRNA-seq) to analyse the cell types and to reveal the sequence of transcriptional events in the emergence of neural crest cells and neural differentiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE214996 | GEO | 2022/10/12

REPOSITORIES: GEO