Structure and functional mapping of the KRAB-KAP1 repressor complex [KAP1_CUT&RUN-seq]

ABSTRACT: We used CUT&RUN to assess how abolition of KRAB binding by KAP1 (through structure-guided mutations in the KAP1-KRAB binding interface) changed the distribution of H3K9me3 epigenetic mark genome-wide.

ORGANISM(S): Homo sapiens

PROVIDER: GSE215014 | GEO | 2022/10/10

REPOSITORIES: GEO