Activation of XBP1 but not ATF6α rescues heart failure induced by persistent ER stress in medaka fish

ABSTRACT: To investigate contribution of different UPR pathways to ER stress-induced abnormal heart phenotype in medaka, we generated constitutive XBP1(S) or ATF6(N) expression medaka lines. We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different genotype medaka hearts.

ORGANISM(S): Oryzias latipes

PROVIDER: GSE215040 | GEO | 2022/10/14

REPOSITORIES: GEO