FLARE: A fast and flexible peak-calling pipeline for identifying RNA editing foci

ABSTRACT: Experimental methods for discovering RNA Binding Protein (RBP) binding sites on target RNAs have recently emerged which employ fusions of RBPs to RNA-editing enzymes (such asAPOBEC1 or ADAR) to “label” mRNA. However, off-target editing, genetic variants and sequencing errors can lead to false positives when using data derived from such approaches, and highlight a need for a robust, statistical approach to prioritizing confident binding sites.

ORGANISM(S): Homo sapiens

PROVIDER: GSE215252 | GEO | 2023/10/18

REPOSITORIES: GEO