The intrinsically disordered region of SPIN1 regulates its function by phase separation [ChIP-seq]

ABSTRACT: As a transcriptional coactivator, SPIN1 has been reported to bind to chromatin.To assess the effect of IDR on chromatin binding, we investigated genome-wide chromatin association of SPIN1-WT or SPIN1-△IDR stably overexpressed cell lines by chromatin immunoprecipitation followed by high-throughput sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE215398 | GEO | 2024/12/19

REPOSITORIES: GEO