JAK2V617F-dependent clonal hematopoiesis drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm

ABSTRACT: In order to understand the mechanisms responsible for lethal JAK2V617F-dependent aortic disease, we performed RNA sequencing in the aorta of 7-week old Jak2V617F HC-EC and control Jak2WT mice

ORGANISM(S): Mus musculus

PROVIDER: GSE215455 | GEO | 2022/10/20

REPOSITORIES: GEO