Transcriptomics

Dataset Information

39

Effects of ACE2 on BMPR2 mutation-mediated defects in gene expression


ABSTRACT: BMPR2 mutation causes pulmonary arterial hypertension (PAH); ACE2 treatment can resolve established BMPR2-mediated PAH. The purpose of this study was to uncover the molecular mechanism behind this. Overall design: Four groups: +/- ACE2 and +/- BMPR2 transgene, two arrays each, each array a pool of three animals.

INSTRUMENT(S): [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

ORGANISM(S): Mus musculus  

SUBMITTER: James West  

PROVIDER: GSE21583 | GEO | 2010-08-25

SECONDARY ACCESSION(S): PRJNA127021

REPOSITORIES: GEO

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