Genomics

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Characterization of de novo promoter variants in autism spectrum disorder with massively parallel reporter assays

ABSTRACT: To functionaly test thousands of promoter based Autism associated de novo variants, we established neural progenitor cells from human embryonic stem cells and performed massively parallel reporter assays to collect transcription rates associated with reference and alternate allele sequences

ORGANISM(S): Homo sapiens

PROVIDER: GSE216129 | GEO | 2023/05/24

REPOSITORIES: GEO

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