IL15 Deficiency in Rats

ABSTRACT: NK cells are a major immune cell in the uterus during pregnancy. IL15 is required for the maturation of these cells, therefore a mutation in the IL15 gene results in a lack of NK cells. In this study, implantation sites were collected from gestational day 9.5 pregnant IL15 deficient or WT Sprague-Dawley Holtzman rats. RNA was collected, and a Clariom S microarray was performed to elucidate differences in gene expression at the developing placenta and uterus between mutants and WT dams.

ORGANISM(S): Rattus norvegicus Rattus

PROVIDER: GSE216395 | GEO | 2023/04/12

REPOSITORIES: GEO