Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Epigenome analysis of liver samples from C57BL/6J, CD1, and Sv129Ev mice in lifelong chronic psychosocial stress (LCPS)

ABSTRACT: Genome wide DNA methylation profiling of liver tissues from 17 months old male mice belonging to either the C57BL/6J, the CD1 or the Sv129Ev strain and exposed to LCPS. The Illumina Infinium Mouse Methylation Beadchip was used to obtain DNA methylation profiles across approximately 285,000 CpGs in liver samples. Samples included 19 C57Bl/6J mice, 12 CD1 mice, and 16 Sv129Ev mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE216631 | GEO | 2023/03/31

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

MicroRNA Expression Data From Sham or BDL CD1 Mouse Liver

Project description:Endothelial cells from normal or cirrhotic CD1 mice were screened for changes in microRNA expression using an Affymetrix array. Total RNA (including microRNA) was extracted from whole liver tissue of CD1 mice, and microRNA expression was assessed using an Affymetrix array. N=1 for each condition (cirrhosis induced by bile duct ligation, control).

2011-08-09 | E-GEOD-31293 | biostudies-arrayexpress

Lack of TRPV1 Channel Modulates Mouse Gene Expression and Liver Proteome with Glucose Metabolism Changes

Project description:To investigate the role of the transient receptor potential channel vanilloid type 1 (TRPV1) channel in hepatic glucose metabolism, we performed proteomics analysis of the liver of C57Bl/6J (WT) and Trpv1 KO mice (n = 4 per group). Liver from Trpv1 KO mice showed significant proteomics changes consistent with enhanced glycogenolysis, as well as increased gluconeogenesis and inflammatory features.

2022-06-21 | MSV000089696 | MassIVE

Mus musculus

Project description:Liver tissue from hormone treated C57BL/6J mice versus pool C57BL/6J mice of chow diet Liver

| PRJNA109557 | ENA

Multi-Omics Analyses Revealed Conserved Aging Signatures in Mice

Project description:Studies on aging have largely included one or two OMICS layers, which may not necessarily reflect the signatures of other layers. Moreover, most aging studies have often compared very young (4-5 wks) mice with old (24 months) mice which does not reflect the aging transition after the attainment of adulthood. Therefore, we aimed to study and compared muti-OMICS aging signatures across key metabolic tissues of mature adults (6 months) and old (24 months) C57BL/6J mice (the most commonly used mouse strain). Here we compared the differentially regulated genes and enriched pathways for transcriptome, proteome and epigenome (H3K27ac, H3K4me3, H3K27me3, DNA methylation) across liver, heart, and quadriceps muscle. The major aging associated pathways cross multiple layers and tissues are decreased RNA metabolism, transcription, and translation at transcript and protein levels however increased potential of transcription at DNA methylation and H3K27ac levels.

2021-11-30 | PXD011142 | Pride

MicroRNA Expression Data From Sham or BDL CD1 Mouse Liver

Project description:Endothelial cells from normal or cirrhotic CD1 mice were screened for changes in microRNA expression using an Affymetrix array.

2011-08-10 | GSE31293 | GEO

Characterization of CD1- and CD1+ porcine blood dendritic cells confirm them as orthologues of the two major mammalian conventional subsets

Project description:Porcine CD1- and CD1+ dendritic cells represent the orthologues of human and mouse cDC1 and cDC2 cellssubsets respectively

2016-12-31 | GSE84029 | GEO

Nrf2 overexpression rescues RPE morphology in mouse models of retinitis pigmentosa [CD1-p40_analysis]

Project description:Contribution of Nrf2 overexpression to the rescue of the RPE and/or photoreceptors in CD1 wild type mice

2021-04-28 | GSE161105 | GEO

R_HAN_01.05 Mice sera fed with prebiotic or antibiotics

Project description:Control diet for C57Bl/6j Mice and effect on microbiota and immunity. Metabolome content of blood of these mice. LC-HRMS/MS C18+.

2019-07-05 | MSV000084062 | MassIVE

Mus musculus

Project description:Liver tissue from the "Four Core Genotype" treated group C57BL/6J mice versus pool C57BL/6J mice of chow diet Liver

| PRJNA109555 | ENA

Psychromonas sp. CD1

Project description:Psychromonas sp. CD1 Genome sequencing and assembly

| PRJNA382855 | ENA