Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Immunomodulatory effects of hydrolyzed Debaryomyces hansenii in Atlantic salmon (Salmo salar L): From the in vitro model to a natural pathogen challenge after seawater transfer

ABSTRACT: Non-Saccharomyces yeast such as Debaryomyces hansenii or its cell wall-components are emerging candidates for novel functional aquafeeds, as they contain several microbe-associated molecular patterns (MAMPs) that can activate and modulate the host’s physiological responses and improve fish health and welfare. RNAseq results showed an upregulation in pathways associated with humoral immunity and complement activation in the liver. Considering these data, LAN6 could be a promising functional candidate for aquafeeds to achieve a more resilient salmon during fish farming.

ORGANISM(S): Salmo salar

PROVIDER: GSE216714 | GEO | 2023/08/29

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Dietary Inclusion of Hydrolyzed Debaryomyces hansenii Yeasts Modulates Physiological Responses in Plasma and Immune Organs of Atlantic Salmon (Salmo salar) Parr Exposed to Acute Hypoxia Stress

Project description:The present work studies the effect of Debaryomyces hansenii yeast-based products on physiological responses in Atlantic salmon exposed to a short-term stress. For this, a control fishmeal-based diet (CD) and experimental diets containing 0.1% of Debaryomyces hansenii were fed to fish for 8 weeks in fresh water. At the end of the feeding experiment, fish were exposed to 1-minute hypoxia stress and samples were collected post-stress

2022-03-08 | GSE189236 | GEO

The farmed Atlantic salmon (Salmo salar) skin-mucus proteome

Project description:Norway is the largest producer and exporter of farmed Atlantic salmon (Salmo salar) worldwide. Skin disorders correlated with bacterial infections represent an important challenge for fish farmers due to the economic losses caused. Little is known about this topic, thus studying the skin-mucus of Salmo salar and its bacterial community depict a step forward in understanding fish welfare in aquaculture. In this study, we used label free quantitative mass spectrometry to investigate the skin-mucus proteins associated with both Atlantic salmon and bacteria. In addition, the microbial temporal proteome dynamics during 9 days of mucus incubation with sterilized seawater was investigated, in order to evaluate their capacity to utilize mucus components for growth in this environment.

2019-07-15 | PXD008838 | Pride

Adaptative response of Debaryomyces hansenii in co-culture with Yarrowia lipolytica

Project description:A comparison between the coculture of Debaryomyces hansenii with Yarrowia lipolytica and the monoculture of Debaryomyces hansenii, was carried out at two hours of culture (12h and 27h), in order to understand the metabolic changes induced in D. hansenii when grown in coculture with Y. lipolytica . The transcriptomic study was carried out using Agilent 8X15k slides with a custom oligoset designed by V. Loux using the Debaryomyces hansenii ORFeome extracted from genolevures database

2018-08-01 | GSE37688 | GEO

Absolute expression level of Debaryomyces hansenii genes

Project description:Total RNA versus genomic DNA hybridization on custom arrays designed for all Debaryomyces hansenii genes Total RNA was collected in mid-log phase from Debaryomyces hansenii cells grown in rich medium (abbreviated CM, in house recipe). RNA was then converted to cDNA, Cy3-labeled and hybridized competitively against Cy5 labeled genomic DNA from Debaryomyces hansenii.

2010-07-06 | E-GEOD-22191 | biostudies-arrayexpress

Absolute expression level of Debaryomyces hansenii genes

Project description:Total RNA versus genomic DNA hybridization on custom arrays designed for all Debaryomyces hansenii genes

2010-07-06 | GSE22191 | GEO

Seawater transfer alters the intestinal microbiota profiles of Atlantic salmon (Salmo salar L.).

Project description: Not available

| S-EPMC5654775 | biostudies-literature

Effects of yeast species and processing on transcriptomic profile and intestinal health of Atlantic salmon (Salmo salar) fed soybean meal-based diets in seawater

Project description:The objective of the current study was to examine the effects of yeasts on intestinal health and transcriptomic profile of Atlantic salmon fed SBM-based diets in seawater. Cyberlindnera jadinii (CJ) and Wickerhamomyces anomalus (WA) yeasts were produced in-house and processed by direct heat-inactivation with spray-drying (ICJ and IWA) or autolyzed at 50 ºC for 16 h (ACJ and AWA), followed by spray-drying. Six diets were formulated, one based on fishmeal (FM), a challenging diet with 30% soybean meal (SBM) and four other diets containing 30% SBM and 10% of each of the four yeast fractions (i.e., ICJ, ACJ, IWA and AWA). The results showed that the inclusion of CJ yeasts reduced loss of supranuclear vacuolization, along with reduction in population of CD8α positive cells present in the lamina propria of fish fed the SBM diet. The CJ yeasts controlled the inflammatory profile of fish fed SBM through up-regulation of pathways related to wound healing and taurine metabolism. Additionally, the WA yeasts dampened the inflammatory profile of fish fed SBM through down-regulation of pathways related to toll-like receptor signaling, C-lectin receptor, cytokine receptor and signal transduction. The results suggest that yeasts could be used as protein ingredients with functional properties in diets for Atlantic salmon.

2022-01-15 | GSE193239 | GEO

A novel betaproteobacterial agent of gill epitheliocystis in seawater farmed Atlantic salmon (Salmo salar).

Project description: Not available

| S-EPMC3299688 | biostudies-literature

RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls

Project description:We found that the fungus, Debaryomyces hansenii (D. hansenii), is enriched in inflamed intestinal tissue from patients of Crohn's disease and its administration to mice impairs colonic wound healing in multiple models of colonic injury and repair. To understand the mechanism, we isolated bone marrow derived macrophages from mice and stimulated them in vitro with a pure isolate of D. hansenii. Total RNA was isolated at multiple time points and assayed for transcriptomic analysis.

2021-04-14 | E-MTAB-9806 | biostudies-arrayexpress

Spleen transcriptomes during behavioural fever in Salmo salar

Project description:The transcriptomic analysis was evaluated using RNA-seq of salmon challenged with the birnavirus IPNv under two different thermal conditions: (a) constant temperature (mean temperature 15 ± 0.9 ºC, “No-Fever”) and (b) temperature gradient (mean temperature 15 ± 7.4 ºC, “Fever”). In parallel, fish in another tank were treated by adding 100 ml virus free cell culture supernatant to the water (mean temperature 15 ± 7.4 ºC, "mock-infected"). We identified a specific transcriptomic signature for each group in the RNA-seq data and identifying a set of key components that control inflammatory modulation during behavioural fever upon viral infection in mobile ectotherms.

2019-12-07 | GSE141554 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data