RNA A>I editing of tau circular RNAs

ABSTRACT: tau circular RNAs undergo Adenosine to inosine editing, which promotes their translation. To map editing sites,we cotransfected expression constructs for tau 7->12 and 10->12 circRNAs with expression constructs for GFP, ADAR1, ADAR2 and ADAR3 in HEK293 cells. RNA from these transfected cells was isolated and A>I editing was identified by A>G changes in the cDNA.

ORGANISM(S): Homo sapiens

PROVIDER: GSE216791 | GEO | 2022/11/08

REPOSITORIES: GEO