Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Histone H3K4me3 epigenetic modification ChIPseq

ABSTRACT: ChIPseq analysis of histone H3 epigenetic modifications - K4me3 - chromatin binding in activated CD4+ T cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE216820 | GEO | 2025/10/13

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Histone H3 epigenetic modifications ChIPseq

Project description:Histone H3 epigenetic modifications ChIPseq

| PRJNA895444 | ENA

Histone H3K4me3 epigenetic modification ChIPseq

Project description:Histone H3K4me3 epigenetic modification ChIPseq

| PRJNA895446 | ENA

Histone H3 epigenetic modifications ChIPseq K27me3

Project description:Histone H3 epigenetic modifications ChIPseq K27me3

| PRJNA895447 | ENA

Histone H3 epigenetic modifications ChIPseq

Project description:ChIPseq analysis of histone H3 epigenetic modification - K27ac - chromatin binding in activated CD4+ T cells

2025-10-13 | GSE216817 | GEO

Histone H3 epigenetic modifications ChIPseq K27me3

Project description:ChIPseq analysis of histone H3 epigenetic modification - K27me3 - chromatin binding in activated CD4+ T cells

2025-10-13 | GSE216818 | GEO

Histone modification and transcription factor ChIPseq of Xenopus laevis epithelial progenitors

2016-02-23 | GSE78176 | GEO

Histone modification and transcription factor ChIPseq of Xenopus laevis epithelial progenitors

Project description:To determine the positions of promoters and enhancers in developing Xenopus laevis epithelial progenitors, we performed ChIPseq on the histone modifications H3K4me3 and H3K27ac. We also performed ChIPseq on the transcription factors foxj1 (in the presence or absence of rfx2), myb (in the presence or absence of multicilin), and rad21. Some embryos were harvested as wild-types; in other experiments, we injected embryos with mRNAs encoding FLAG-foxj1 (with and without rfx2 morpholino) or GFP-myb (with and without an inducible form of multicilin (mcidas-HGR)). We then isolated epithelial progenitors surgically and, when injected with multicilin, induced at mid-stage 11. We then harvested chromatin at 9 hours after induction (roughly stage 18) and performed ChIPseq using antibodies against endogenous targets (H3K4me3, H3K27ac, rad21) or protein tags (FLAG, GFP). We then sequenced these libraries, aligned the reads to the X. laevis genome (version 9.1) with bwa mem and called peaks with HOMER, using input as background.

2016-02-23 | E-GEOD-78176 | biostudies-arrayexpress

Histone H3 epigenetic modifications

Project description:Histone H3 epigenetic modifications

| PRJNA895442 | ENA

T1DGC H3K4me3 ChIPseq

Project description:T1DGC H3K4me3 ChIPseq

| PRJNA398437 | ENA

Histone H3K4me3 modification is a transgenerational epigenetic signal for lipid metabolism in Caenorhabditis elegans.

Project description:As a major risk factor to human health, obesity presents a massive burden to people and society. Interestingly, the obese status of parents can cause progeny's lipid accumulation through epigenetic inheritance in multiple species. To date, many questions remain as to how lipid accumulation leads to signals that are transmitted across generations. In this study, we establish a nematode model of C. elegans raised on a high-fat diet (HFD) that leads to measurable lipid accumulation, which can transmit the lipid accumulation signal to their multigenerational progeny. Using this model, we find that transcription factors DAF-16/FOXO and SBP-1/SREBP, nuclear receptors NHR-49 and NHR-80, and delta-9 desaturases (fat-5, fat-6, and fat-7) are required for transgenerational lipid accumulation. Additionally, histone H3K4 trimethylation (H3K4me3) marks lipid metabolism genes and increases their transcription response to multigenerational obesogenic effects. In summary, this study establishes an interaction between a network of lipid metabolic genes and chromatin modifications, which work together to achieve transgenerational epigenetic inheritance of obesogenic effects.

| S-EPMC8828817 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data