Genomics

Dataset Information

0

Acute effects of liraglutides on gene expression in the hearts of mice with experimental myocardial infarction


ABSTRACT: Glucagon-like peptide-1 receptor (GLP-1R) agonists reduce the rates of major cardiovascular events, including myocardial infarction in people with type 2 diabetes, and decrease infarct size while preserving ventricular function in preclinical studies. Nevertheless, the precise cellular sites of GLP-1R expression that mediate the cardioprotective actions of GLP-1 in the setting of ischemic cardiac injury are uncertain. Here, cardiac gene expression profiles regulated by liraglutide were examined using RNA-Seq to interrogate mouse atria and both non-infarcted and non-infarcted ventricular tissue after acute coronary artery ligation.

ORGANISM(S): Mus musculus

PROVIDER: GSE217736 | GEO | 2022/11/21

REPOSITORIES: GEO

Similar Datasets

2020-12-24 | GSE163744 | GEO
2021-03-16 | GSE168937 | GEO
2022-12-09 | GSE211105 | GEO
2023-08-09 | GSE240409 | GEO
2023-08-09 | GSE240406 | GEO
2023-10-11 | PXD037472 | Pride
2021-03-23 | PXD022212 | Pride
2022-08-29 | GSE202453 | GEO
2022-08-29 | GSE202452 | GEO
2023-03-02 | PXD037495 | Pride