Inhibition of γ-glutamyl transpeptidase suppresses LPS induced asthma exacerbation in a mouse model

ABSTRACT: To investigate the role of γ-glutamyltranspeptidase in severe asthma, we established an OVA/ LPS-induced asthma model. Inflammation analysis and second-generation sequencing revealed the mechanism by which inhibition of γ-glutamyltranspeptidase inhibited LPS-induced asthma exacerbation in mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE217834 | GEO | 2023/07/05

REPOSITORIES: GEO