A druggable signaling hub of choroid plexus immune-secretory function

ABSTRACT: Integrated multi-omics investigation of novel rat models of acquired hydrocephalus, Blood or bacteria in CSF trigger similar choroid plexus (ChP) immune-secretory responses, Crosstalk between ChP immune and epithelial cells drives CSF hypersecretion and ventriculomegaly, Repurposed systemic immunomodulators ameliorate acquired hydrocephalus, Identification of a druggable hub of ChP function relevant for multiple neurological diseases.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE218143 | GEO | 2023/02/17

REPOSITORIES: GEO