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A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis independent role for p53 in self-renewal

ABSTRACT: Analysis of differentially expressed genes in human Cord Blood cells cultured for 4 days and sorted into CD34+CD90+ and CD34+CD90- fractions. The objective for the experiment was to identify genes related to p53 and DNA damage response pathways

ORGANISM(S): Homo sapiens

PROVIDER: GSE21830 | GEO | 2010/06/29

SECONDARY ACCESSION(S): PRJNA126909

REPOSITORIES: GEO

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A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis independent role for p53 in self-renewal

Project description:Analysis of differentially expressed genes in human Cord Blood cells cultured for 4 days and sorted into CD34+CD90+ and CD34+CD90- fractions. The objective for the experiment was to identify genes related to p53 and DNA damage response pathways Total RNA was isolated from at least 10000 cells after 4 days of culture and sorting

2010-07-29 | E-GEOD-21830 | biostudies-arrayexpress

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