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Effects of pharmacological manipulations of the NA system on the transcriptional stress response in the mouse hippocampus

ABSTRACT: Here, we extensively characterize noradrenaline (NA) mediated transcriptomic response during acute stress in the mouse hippocampus. Combining for the first time bulk mRNA-sequencing and selective pharmacological manipulations of the NA system. We show that the NA mediates robust stress associated transcriptomic alterations across the dorsal and ventral hippocampus via β-adrenergic receptors

ORGANISM(S): Mus musculus

PROVIDER: GSE218315 | GEO | 2023/02/02

REPOSITORIES: GEO

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