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PARP1 gene knockout suppresses expression of DNA Base Excision Repair genes

ABSTRACT: PARP1 is a member of various DNA repair pathways - main target for anti-cancer treatment. We evaluated the effect of topotecan and TDP1 Inhibitor in HEK293 wild-type and PARP1 knockout cells on the gene expression

ORGANISM(S): Homo sapiens

PROVIDER: GSE218871 | GEO | 2022/12/01

REPOSITORIES: GEO

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