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Influence of Sox4 on chromatin accessibility of adult hepatocytes [EV and Sox4]

ABSTRACT: Recent studies have demonstrated that hepatocytes can be reprogrammed into biliary epithelial cell-like cells. An earlier work in our laboratory nominated Sox4 as an initiation factor of this reprogramming event To investigate the effect of Sox4 on the change of chromatin landscape of hepatocytes, we performed ATAC-seq of exogenously Sox4-expressed hepatocytes.

ORGANISM(S): Mus musculus

PROVIDER: GSE219052 | GEO | 2023/11/28

REPOSITORIES: GEO

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