Programmed Death Ligand 1 in Tumor Margins with Implications of Regulation by Interferon Gamma, and a Novel Immuno-Oncologic Transcriptional Signature for Malignant Transformation

ABSTRACT: Basic analysis of 5 pairs of tumor margin and invasive OSCC tumor tissue using basic nsolver analysis showed, PD-L1 and IFN-γ 6 gene signature to be higher in morphologically normal epithelial tumor margin than in dysplastic tumor margin, yet the invasive OSCC area was the highest in PD-L1 and IFN-γ 6 gene signature. It also demosntrates 38 significant Immuno oncologic gene signature for maligant transformation relative to tumor margins.

ORGANISM(S): Homo sapiens

PROVIDER: GSE219053 | GEO | 2023/12/31

REPOSITORIES: GEO