Epigenetic regulation of SARS-Cov-2 spike protein modulates cellular viability and nascent RNA transcription in neuronal cells

ABSTRACT: To investigate the effect of SARS-CoV-2 spike RBD on the transcription of nascent RNA in nerve cells, we treated SH-SY5Y cells with RBD and extracted nascent RNA for RNA-seq. We then performed gene expression profiling analysis using data obtained from RNA-seq of SH-SY5Y cells at two time points.

ORGANISM(S): Homo sapiens

PROVIDER: GSE220046 | GEO | 2023/06/03

REPOSITORIES: GEO