Single-cell RNA-Seq of fibroblasts derived from one patient with idiopathic pulmonary fibrosis.
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ABSTRACT: Fibroblast appears to play a central role in the pathogenesis of IPF. We performed scRNA-seq of fibroblast from IPF patient, and evaluate its cell-cell interaction combined with the engrafted bronchial BCs. Our study reveals that engrafted BCs isolated from small bronchi can mediate anti-fibrotic effect by interacting with adjacent fibroblasts.
ORGANISM(S): Homo sapiens
PROVIDER: GSE220743 | GEO | 2023/11/01
REPOSITORIES: GEO
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