Reprogramming of rhythmic liver metabolism by intestine clock
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ABSTRACT: To assess potential impact of intestine clock on the rhythmicity of peripheral tissues (liver, kidney and WAT), mice with Bmal1 specifically deleted in the intestine (Bmal1-iKO mice, showing loss of clock function in the intestine) were generated. We collected liver, kidney and WAT samples from Bmal1-iKO and control (Bmal1-flox) mice every 4 hours throughout a light/dark cycle, and subsequently performed transcriptomic analyses.
ORGANISM(S): Mus musculus
PROVIDER: GSE220864 | GEO | 2023/06/01
REPOSITORIES: GEO
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