Identify a panel of transcripts that exhibited differential expression between spinal cord motor neurons (spMNs) with low and high regenerative abilities

ABSTRACT: The mammalian neurons in the central nervous system (CNS) fail to regenerate their axons after injury, while the adult peripheral nervous system (PNS) neurons can regenerate their axons robustly. Promoting the intrinsic regenerative capacity of CNS neurons after injury is potential way to solve this difficulty. For this purpose, we have identified a panel of transcripts that exhibited differential expression between spinal cord motor neurons (spMNs) with low and high regenerative abilities by using retrograde tracing and single-cell RNA sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE221115 | GEO | 2022/12/30

REPOSITORIES: GEO