Superior Expansion of Zone 2 Hepatocytes in Pregnancy

ABSTRACT: We found that the hepatocyte proliferation wave initiated from zone 1/2 to zone 2/3 during early-to-late pregnancy, resulting in the generation of most new hepatocytes in zone 2. By single-cell RNA sequencing, we identified that Ccnd1 was highly enriched in zone 2.

ORGANISM(S): Mus musculus

PROVIDER: GSE221375 | GEO | 2023/11/30

REPOSITORIES: GEO