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Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Wac B Cell Conditional Knockout Activated B Cells Transcriptomes

ABSTRACT: To investigate the function of Wac in the regulation of B cell activation and plasmablasts differentiation, we used Cre-Loxp system to generate Wac conditional knockout mice (Wacf/f Cd19cre/+). We then performed gene expression profiling analysis using data obtained from RNA-seq of in vitro LPS activated wild-type and Wac knockout B cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE221490 | GEO | 2025/12/04

REPOSITORIES: GEO

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