Effects of dopamine on HIV latently-infected U1 macrophage cell line

ABSTRACT: U1 monocytic cell line was cloned from U937 cells that survived an infection with Human Immunodeficiency Virus HIV-1 and bear integration sites, serving as one of the most studied HIV latent models. Under the hypothesis that the hyperdopaminergic environment of the brain of substance users affects HIV-infected cells and latency, we tested the effects of Dopamine and two dopamine receptors that were identified as able to signal changes ininnate immune cells, DRD1 and DRD4.

ORGANISM(S): Homo sapiens

PROVIDER: GSE221531 | GEO | 2022/12/21

REPOSITORIES: GEO