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Human hepatocytes can give rise to intrahepatic cholangiocarcinomas

ABSTRACT: To determine the transcriptomic similarity of undifferentiated carcinomas (UDCs) and intrahepatic cholangiocarcinomas (iCCAs) generated from primary human hepatocytes (phHeps) by oncogene expression and transplantation into immue-deficient mice with liver injury to iCCAs and hepatocellular carcinomas (HCCs) resected from patients.

ORGANISM(S): Homo sapiens

PROVIDER: GSE221589 | GEO | 2024/01/12

REPOSITORIES: GEO

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