Transcriptomic characterization of control and drug-treated APOB-mutant organoids to study steatosis-resolving drug effects

ABSTRACT: We treated APOB-mutant organoids with different anti-NAFLD drug candidates that were effective at resolving steatosis. To understand the mechanisms of drug action and adverse drug effects we performed bulk RNA-sequencing on drug-treated and vehicle-treated APOB mutant organoids.

ORGANISM(S): Homo sapiens

PROVIDER: GSE221705 | GEO | 2023/02/23

REPOSITORIES: GEO