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Characterizing the transcriptional role of L-DOPA and antimycin A on mitichondrial regulation in Cryptococcus neoformans using a cir1 knockout strain

ABSTRACT: Proper mitochondrial function is critical for the ability of the fungal pathogen Cryptococcus neoformans to cause disease. Mitochondrial dysfunction of WT cells treated with antimycin A or L-DOPA, or on cells lacking Cir1 is evident from this dataset. These experiments revealed influences on transcript levels of genes encoding Fe-S cluster assembly components and the response to oxidative stress in Cryptococcus neoformans.

ORGANISM(S): Cryptococcus neoformans var. grubii H99

PROVIDER: GSE222564 | GEO | 2024/04/07

REPOSITORIES: GEO

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Transcriptome analysis of the iron regulatory transcription factors in Cryptococcus neoformans in response to iron availability

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