Transcriptomics

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Gene expression profile at single cell levels of the cells from the controls and tau P251L Drosophila brain.


ABSTRACT: Tau protein has been implicated in the pathology of Alzheimer's disease and related disorders. We CRISPR engineered an endogenous model of tauopathy by knocking in a pathogenic human tau mutation, tau P301L, in Drosophila, tau P251L KI. We used single cell RNA sequencing to identify the differentially expressed genes or pathways.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE223345 | GEO | 2024/02/26

REPOSITORIES: GEO

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