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MiRNA expression data from A549 exposed to formaldehyde

ABSTRACT: We are investigating the miRNA expression profiles of human lung cells to gaseous formaldehyde We used microarrays to detail the global programme of miRNA expression upon response to formaldehyde

ORGANISM(S): Homo sapiens

PROVIDER: GSE22365 | GEO | 2010/10/01

SECONDARY ACCESSION(S): PRJNA127677

REPOSITORIES: GEO

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miRNA expression data from A549 exposed to formaldehyde

Project description:We are investigating the miRNA expression profiles of human lung cells to gaseous formaldehyde We used microarrays to detail the global programme of miRNA expression upon response to formaldehyde A549 cells were grown to confluency and exposed to formaldehyde or mock-treated. RNA was collected 9 hrs after exposure.

2010-10-01 | E-GEOD-22365 | biostudies-arrayexpress

Expression data from rosette leaves of Arabidopsis thaliana which has formaldehyde tolerance (rmpA/rmpB double transgenic) upon formaldehyde exposure

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mRNA expression data from A549 exposed to fresh or aged urban air mixtures

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Expression data from rosette leaves of Arabidopsis thaliana wild type upon formaldehyde exposure

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mRNA expression data from A549 exposed to fresh or aged urban air mixtures

Project description:We are investigating the mRNA expression profiles of human lung cells to gaseous urban mixtures We used microarrays to compare the global mRNA expression profiles upon response to fresh against aged urban mix Keywords: dose A549 cells were grown to confluency and exposed to fresh urban mix, aged urban mix, or mock-treated. RNA was collected 9 hrs after exposure.

2011-02-01 | E-GEOD-23735 | biostudies-arrayexpress

Formaldehyde-induced changes in microRNA signaling [Affymetrix]

Project description:In addition to gaining knowledge on in vivo miRNA responses to formaldehyde, we set out to relate these miRNA responses to transcriptional profiles modified by formaldehyde. Rats were exposed by inhalation to either 0 or 2 ppm formaldehyde (6 hours/day) for 28 days. Genome-wide transcriptional profiles and associated signaling pathways were assessed within the nasal respiratory mucosa and circulating mononuclear white blood cells (WBC).

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Expression data from TK6 exposed to low-dose metals

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Activation of inflammation and nfkb signaling in infants born to arsenic exposed mothers

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Expression data from male cynomolgus macaques exposed to 6 ppm formaldehyde

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Epigenetics effects of formaldehyde inhalation exposure

Project description:We set out to test the hypothesis that formaldehyde inhalation exposure significantly alters miRNA expression profiles within the nasal epithelium of nonhuman primates. Here, cynomolgus macaques were exposed to 0, 2, and 6 ppm formaldehyde for 6 hours/day across two consecutive days. RNA was extracted from the nasal maxilloturbinate region, a direct target of formaldehyde inhalation exposure. Genome-wide miRNA expression levels were assessed using microarrays. Cynomolgus macaques (Macaca fascicularis) were exposed to 0, 2 and 6 ppm formaldehyde for 6 hours/day across two consecutive days using whole body exposure chambers. RNA was extracted from the nasal maxilloturbinate region, a direct target of formaldehyde inhalation exposure. Genome-wide miRNA expression levels were assessed using microarrays.

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