Circular RNA expression profile in mitochondria fractions of liver tumour-initiating cells

ABSTRACT: Tumour-initiating cells (TICs), also termed as cancer stem cells, contribute to tumour initiation, metastasis, progression and drug resistance. Metabolic reprogramming is a cancer hallmark and plays vital roles in liver tumorigenesis. However, the role of metabolic reprogramming in TICs remains poorly explored.Here we isolated mitochondria from liver TICs and non-TICs, and detected the expression levels of mitochondrial encoded circRNAs in TICs and non-TICs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE223661 | GEO | 2023/01/25

REPOSITORIES: GEO