Effect of NMTi on senescence model systems

ABSTRACT: To examine effects of NMT inhibition on senescence transcriptional signatures we treated IMR90 ER:RAS cells with either IMP1088 (300nM) or DDD86481 (1.5uM) for 72h 7 days after induction with 4-OHT treatment. Transcriptional analysis was performed 3 days after drug treatment and 10 days after senescence induction.

ORGANISM(S): Homo sapiens

PROVIDER: GSE224071 | GEO | 2023/09/28

REPOSITORIES: GEO