MFAP5 regulates skin scar formation and fibroblast activation

ABSTRACT: A subset of human skin fibroblasts are phagocytic. To investigate the gene expression changes between phagocytosing and non-phagocytosing fibroblasts, fibroblasts were incubated with apoptotic human dermal microvascular endothelial cells expressing green fluorescent protein or no treatment. Treated fibroblasts were then collected after 8 hours and sorted by FACS to identify phagocytic and non-phagocytic fibroblasts. We then performed gene expression profiling analysis using data obtained from RNA-seq of these three groups of cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE224202 | GEO | 2023/06/01

REPOSITORIES: GEO