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Transcriptional profiling of Rat PFC 2 hours after the beginnig of stress

ABSTRACT: We performed microarray transcriptional profiling of rat prefrontal cortex 2 hours after the beginnig of acute inescapable footshock (FS) stress Samples were collected from rats exposed to FS stress and sacrificed 2 hours after the beginnig of 40-minutes stress section and from controls left undisturbed in their cage

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE224313 | GEO | 2023/02/07

REPOSITORIES: GEO

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Transcriptional profiling of Rat PFC 24 hours after the beginnig of stress

Project description:We performed microarray transcriptional profiling of rat prefrontal cortex 24 hours after the beginnig of acute inescapable footshock (FS) stress Samples were collected from rats exposed to FS stress and sacrificed 24 hours after the beginnig of 40-minutes stress section and from controls left undisturbed in their cage

2023-02-07 | GSE224314 | GEO

Transcriptional profiling of Rat PFC after footshock stress

Project description:We performed microarray transcriptional profiling of rat prefrontal cortex after acute inescapable footshock (FS) stress Samples were collected from rats exposed to FS stress and sacrificed immediately after the 40-minutes stress section and from controls left undisturbed in their cage

2023-02-07 | GSE224312 | GEO

Gene expression profiling of C57BL/6 mouse lung tissue with various treatments using the MA11 array

Project description:Flaxseed (FS), a nutritional supplement consisting mainly of omega-3 fatty acids and lignan phenolics, has potent anti-inflammatory, anti-fibrotic and antioxidant properties. We have shown that dietary FS supplementation ameliorates oxidative stress and inflammation in experimental models of acute and chronic lung injury in mice resulting from diverse toxicants. The development of lung tissue damage in response to direct or indirect oxidant stress is a complex process, associated with changes in expression levels of a number of genes. We therefore postulated that flaxseed may modulate gene expression of vital signaling pathways, thus interfering with the development of tissue injury. We evaluated gene expression in lungs of flaxseed-fed (10% FS) mice under unchallenged, control conditions and 48hrs post-radiation treatment (13.5 Gy). Gene expression levels in lung tissues were analyzed using three arrays for each sample, whereby a total of 28,800 genes were evaluated. C57BL/6 black mice were fed a 10% flaxseed diet for 21 days and/or given 13.5Gy thoracic radiation and sacrificed 48hrs post radiation.

2012-03-14 | E-GEOD-36422 | biostudies-arrayexpress

Gene expression profiling of C57BL/6 mouse lung tissue with various treatments using the MA07 array

2012-03-14 | E-GEOD-36420 | biostudies-arrayexpress

Gene expression profiling of C57BL/6 mouse lung tissue with various treatments using the MA10 array

2012-03-14 | E-GEOD-36421 | biostudies-arrayexpress

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Project description:Tet-ZFP36L1 in 6 hours and 24 hours

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DH06 Adrenal ACTH Sus scrofa

Project description:Large White and Meishan pigs were either non-treated or injected with mammalian 1-24 ACTH (Immediate Synachten, Novartis France) at the dose of 250 µg per animal. Pigs were sacrificed either immediately after capture from their home cage (non-treated animals) or 1 hour following ACTH injection. Adrenal glands were immediately collected from pigs and frozen on dry ice and then stored at -80°C until RNA isolation. Keywords: stress response, adrenal, gene expression, pig

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Transcription profiling by array of mouse amygdala to detect transcripts regulated by psychological stress

Project description:Detection of transcripts regulated by psychological stress in mouse amygdala. Prior to experiments mice were kept undisturbed for one week in their home cages. Restraint stress was performed during the light period of the circadian cycle. Control animals were left undisturbed and stressed animals were subjected to a six hour restraint stress session in a separate room. The mice were placed in their home cages in wire mesh restrainers secured at the head and tail ends with clips

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The Neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory.

Project description:We performed an RNA Sequencing experiment on dorsal hippocampal tissue from four groups of animals: Baf53b+/- homecage (Baf53b+/- HC); Baf53b+/- behavior (Baf53b+/- Beh); wildtype homecage (WT HC); and wildtype behavior (WT Beh). Homecage animals were sacrificed directly from the animal's cage. Behavior animals were sacrificed thirty minutes following Object Location Memory training. The objective of this study was to examine activity regulated gene expression following a learning event (HC vs Beh) in wildtype and Baf53b+/- mutant mice.

2013-03-24 | GSE44229 | GEO

Changes in total RNA in BK deficient mice after 4h sleep deprivation [individuals]

Project description:Animals deficient for the alpha subunit of the large conductance calcium dependent potassium channel (BK) were sleep deprived for 4 hours and compared to wildtype littermates as well as animals (wildtype littermate and BK deficient) left undisturbed for the same time.

2019-07-31 | GSE132074 | GEO

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