Transcriptomics

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Loss of interleukin-1 beta is not protective in the lupus-prone NZM2328 mouse model


ABSTRACT: RNA-sequencing analysis identified upregulation of TNF and IL-17 signaling pathways specifically in females lacking IL-1β. Increases in these signaling pathways are also found in female patients with lupus nephritis, suggesting clinical relevance for upregulation of these pathways.

ORGANISM(S): Mus musculus

PROVIDER: GSE224549 | GEO | 2023/04/30

REPOSITORIES: GEO

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