Transcriptomics

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Expression profile of primary murine astrocyte-enriched cultures (AEC) exposed to oxygen-glucose deprivation


ABSTRACT: Microarray analysis was used to identify genes that fluctuated by oxygen-glucose deprivation of mouse astrocytes. Astrocyte-enriched cultures were generated from mixed glial cultures of mice and compared to control samples with 15 hours of oxygen-glucose deprivation. The results showed that 173 genes were upregulated with Fold change >10, P < 0.05. Both Nr4a1 and Nr4a3, which is an orphan nuclear receptor subfamily and known as an immediate early gene, were upregulated.

ORGANISM(S): Mus musculus

PROVIDER: GSE224577 | GEO | 2023/02/11

REPOSITORIES: GEO

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