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Synthetic TLR7/8 agonist bottlebrush prodrugs enable tumor-selective immune stimulation following systemic administration

ABSTRACT: We used single cell RNA sequencing to understand how the tumor microenvironment changes with TLR7/8 agonist bottlebrush

ORGANISM(S): Mus musculus

PROVIDER: GSE224626 | GEO | 2023/04/26

REPOSITORIES: GEO

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Stimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ)

Project description:The purpose of this experiment was to assess the genes upregulated when pDCs were stimulated with TLR7 agonist imiquimod and TLR9 agonist CpG C.

2016-03-17 | GSE79272 | GEO

Stimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ)

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2016-03-17 | E-GEOD-79272 | biostudies-arrayexpress

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Project description:TLR3, TLR7, and TLR9 stimulation induces many mouse inflammatory and autoimmune cytokines or immune receptors DRGN were cultures 5 days prior to a 16 hour stimulation - Three separate studies were analyzed for inflammatory response

2011-03-02 | E-GEOD-27579 | biostudies-arrayexpress

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Project description:TLR3, TLR7, and TLR9 stimulation induces many mouse inflammatory and autoimmune cytokines or immune receptors

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