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Cooperativity between H3-K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars (CUT&RUN)

ABSTRACT: PDGFRA and H3.3 mutations cooperate in an iPSC-based model of diffuse midline glioma to alter tumor biology.

ORGANISM(S): Homo sapiens

PROVIDER: GSE225490 | GEO | 2023/06/14

REPOSITORIES: GEO

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