Dataset Information


Genome-wide maps of Sin3A and Sin3B binding in C2C12 myoblasts and differentiated myotubes

ABSTRACT: Sin3A and Sin3B bind to distinct and overlapping target sites. Sin3 proteins bind to distinct sites in cycling myoblasts whereas there is a converge of Sin3A and Sin3B proteins to sites in differentiated myotubes. We identified a subset of Sin3 target genes involved in muscle differentiation and physiology and showed that conditional ablation of Sin3 proteins in vivo in mouse results in sarcomere defects Overall design: Examination of Sin3A and Sin3B binding during myogenesis

INSTRUMENT(S): Illumina Genome Analyzer (Mus musculus)

ORGANISM(S): Mus musculus  

SUBMITTER: Brian Dynlacht  

PROVIDER: GSE22554 | GEO | 2011-01-01



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