Transcriptomics

Dataset Information

16

Wilms Tumor-1 (WT-1) and its candidate target genes in gliomagenesis


ABSTRACT: WT-1 is a zinc-finger transcription factor with important roles during development. WT-1 is associated with the development of tumors of varied origins. Our lab has previously demonstrated aberrant expression of WT-1 in tumor cells. Necessity of WT-1 for tumor cell growth- in vitro & in vivo- was also shown. Overall design: Human glioma U251 cells were treated with Oligofectamine (CTRL), Oligofectamine + non-targeting siRNA control (SCR) or Oligofectamine+ si-WT1 siRNA (Si). Biological triplicates were run on microarrays.

INSTRUMENT(S): [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

ORGANISM(S): Homo sapiens  

SUBMITTER: William C Broaddus  

PROVIDER: GSE22578 | GEO | 2011-06-24

SECONDARY ACCESSION(S): PRJNA128411

REPOSITORIES: GEO

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