Chromatin profiling of GM12878 cells with and without a predicted enhancer element

ABSTRACT: We test the predicted interferon-inducible enhancer activity of a LINE within the first intron of the IFNAR1 gene (IFNAR1.L1M2a) by knocking out the predicted enhancer using CRISPR, and assessing chromatin and polymerase II occupancy in untreated and interferon beta-treated conditions compared to wildtype cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE225824 | GEO | 2023/03/07

REPOSITORIES: GEO