TCF7L1 controls tuft cell differentiation

ABSTRACT: To study the functions of Tcf7l1 during gut development, we have ablated Tcf7l1 specifically in the intestinal epithelium using Shh-Cre. To determine transcriptional changes upon loss of Tcf7l1, we have isolated EpCAM-positive epithelial cells from mouse embryos using fluorescence activated cell sorting (FACS) and performed RNA-sequencing analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE226187 | GEO | 2023/06/14

REPOSITORIES: GEO