The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition [DNA methylation]

ABSTRACT: This study comprehensively evaluated the landscape of genetic and epigenetic events that predispose to synchronous bilateral Wilms tumor (BWT). We performed whole exome or whole genome sequencing, total-strand RNA-seq, and DNA methylation analysis using germline and/or tumor samples from 68 patients with BWT from St. Jude Children’s Research Hospital and the Children’s Oncology Group.

ORGANISM(S): Homo sapiens

PROVIDER: GSE226234 | GEO | 2023/11/10

REPOSITORIES: GEO